Anderson Center is located on 350-acre historic Tower View campus, built by Dr. Alexander Pierce Anderson between 1915 and 1921, on the western edge of Red Wing, Minnesota. Tower View's original buildings are listed on the National Register of Historic Places. Anderson Center features a large sculpture garden, and is adjacent to the Cannon Valley Bike Trail, a 20-mile biking and walking trail that runs from Cannon Falls to Red Wing.

Anderson Center is approximately 45 minutes southeast of Minneapolis and St. Paul, and 5 minutes northwest of the small but charming town of Red Wing. Transportation is provided between the Center and the Minneapolis-St. Paul Airport (MSP) on the first and last day of residencies only. Residents who choose to drive will have access to private parking on the property. Residents without cars can either use one of Anderson's bicycles to ride into town (about 5 miles) or, often, can get a ride in with another resident.

The community of Red Wing, Minn., (pop. 16,000) is nestled amidst the scenic bluffs of the upper Mississippi River. The town is settled on the traditional and sacred land of the Bdewakantunwan Dakota & Wahpekute bands of the Eastern Dakota people. The City of Red Wing is named after Tatanka Mani (Walking Buffalo), a leader of the Bdewakantunwan Dakota in the upper Mississippi Valley who wore a ceremonial swan’s wing dyed in brilliant red. In 1815, Tatanka Mani and his people moved their village south to a place they called Khemnichan (Hill, Wood, & Water) in present-day downtown Red Wing. Euro-American immigrants who met him as they advanced into the region in the early nineteenth century came to know him and his village as “Red Wing.”

Since its settlement and eventual incorporation in 1857, Red Wing established itself as a center for agriculture, industry, tourism, medical care, technology, and the arts. The Red Wing Shoe Company and its iconic brands, in particular, continue to have a significant impact on the community’s economic, business, and community development climates. Natural resources abound with Red Wing's riverfront, winding paths through the majestic bluffs, bike trails, and 35 city parks. The Prairie Island Indian Community is located northwest of the city. Frontenac State Park is to the southeast on Lake Pepin. Minnesota State College Southeast Technical’s Red Wing campus is known for its string and brass instrument repair programs. The MN Dept. of Corrections also operates a large juvenile residential facility in Red Wing.

Other amenities include a destination bakery, a chocolate shop, coffee shops, restaurants, the flagship Red Wing Shoe Company store, Goodhue County Historical Society Museum, the Red Wing Stoneware & Pottery store, the Pottery Museum of Red Wing, a Duluth Trading store, the Red Wing Marine Museum, a Target, several pharmacies, a plant nursery & garden center, a Mayo Health System Hospital, a small independent bookstore, and a public library (the Center has arranged for residents to have access to a library card for their month at the Center)

Other key community stakeholders include the historic Sheldon Theatre, the Red Wing Arts Association, Red Wing YMCA, Rise Up Red Wing, Hispanic Outreach of Goodhue County, Red Wing Area Friends of Immigrants, Red Wing Area Women’s Network, Live Healthy Red Wing, Artreach, Red Wing Artisan Collective, Evening Start Quilt Guild, the Artist Sanctuary, Pier 55 Red Wing Area Seniors, Big Turn Music Festival, Red Wing AAUW, Red Wing Environmental Learning Center, Red Wing Area Girl Scouts, Red Wing Public Schools, Tower View Alternative High School, and Universal Music Center, as well as several City boards, commissions, and departments (such as the Human Rights Commission and the Arts & Culture Commission).